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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AMPD2
All Species:
4.55
Human Site:
T334
Identified Species:
9.09
UniProt:
Q01433
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01433
NP_004028.3
879
100688
T334
R
G
V
V
H
V
Y
T
R
R
E
P
D
E
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093312
879
100639
T334
Q
G
V
V
H
V
Y
T
R
R
E
P
D
E
H
Dog
Lupus familis
XP_852599
799
92011
H309
L
S
S
K
F
Q
M
H
V
L
L
N
E
M
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBT5
798
92005
H309
L
S
S
K
F
Q
M
H
V
L
L
N
E
M
K
Rat
Rattus norvegicus
Q02356
824
94769
I312
V
N
V
L
M
A
L
I
I
N
G
P
I
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700028
819
94934
P311
M
A
L
I
I
N
G
P
V
K
S
F
C
Y
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727741
774
89333
C285
S
F
C
Y
R
R
L
C
Y
L
S
S
K
Y
Q
Honey Bee
Apis mellifera
XP_623550
773
88695
R283
P
L
K
S
F
C
Y
R
R
L
S
Y
L
S
S
Nematode Worm
Caenorhab. elegans
NP_001040752
803
92339
L311
A
M
I
V
D
G
P
L
K
S
F
C
F
R
R
Sea Urchin
Strong. purpuratus
XP_792615
845
97202
K312
E
N
Q
E
K
L
E
K
N
E
P
I
E
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O80452
839
95111
D314
V
H
V
F
A
N
K
D
A
K
E
D
L
F
P
Baker's Yeast
Sacchar. cerevisiae
P15274
810
93283
D312
K
M
I
S
I
S
S
D
G
P
A
K
S
F
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.6
89.5
N.A.
88.6
91.4
N.A.
N.A.
N.A.
N.A.
72.5
N.A.
52.5
54
46.8
48.3
Protein Similarity:
100
N.A.
99.8
90.2
N.A.
89.3
92
N.A.
N.A.
N.A.
N.A.
82
N.A.
67.4
65.9
60.9
63.2
P-Site Identity:
100
N.A.
93.3
0
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
0
N.A.
0
13.3
6.6
0
P-Site Similarity:
100
N.A.
100
6.6
N.A.
6.6
26.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
0
13.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.5
41.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.4
57.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
9
9
0
0
9
0
9
0
0
0
17
% A
% Cys:
0
0
9
0
0
9
0
9
0
0
0
9
9
0
0
% C
% Asp:
0
0
0
0
9
0
0
17
0
0
0
9
17
0
0
% D
% Glu:
9
0
0
9
0
0
9
0
0
9
25
0
25
17
0
% E
% Phe:
0
9
0
9
25
0
0
0
0
0
9
9
9
17
0
% F
% Gly:
0
17
0
0
0
9
9
0
9
0
9
0
0
0
0
% G
% His:
0
9
0
0
17
0
0
17
0
0
0
0
0
0
17
% H
% Ile:
0
0
17
9
17
0
0
9
9
0
0
9
9
0
0
% I
% Lys:
9
0
9
17
9
0
9
9
9
17
0
9
9
9
17
% K
% Leu:
17
9
9
9
0
9
17
9
0
34
17
0
17
9
0
% L
% Met:
9
17
0
0
9
0
17
0
0
0
0
0
0
17
0
% M
% Asn:
0
17
0
0
0
17
0
0
9
9
0
17
0
0
0
% N
% Pro:
9
0
0
0
0
0
9
9
0
9
9
25
0
0
9
% P
% Gln:
9
0
9
0
0
17
0
0
0
0
0
0
0
0
9
% Q
% Arg:
9
0
0
0
9
9
0
9
25
17
0
0
0
9
17
% R
% Ser:
9
17
17
17
0
9
9
0
0
9
25
9
9
9
17
% S
% Thr:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% T
% Val:
17
0
34
25
0
17
0
0
25
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
25
0
9
0
0
9
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _